U225 intradermal injector
Delivers active ingredients into the skin rather than onto it. The injector works automatically, so every injection lands at the same depth.
In mesotherapy active ingredients are brought directly into the skin. The U225 does that automatically and evenly; the needle is mounted separately from the syringe, which improves the precision of the delivery. There are various skin boosters, including a depigmentation booster for face, neck and décolleté.
The therapist chooses the settings based on your skin, your health, the treatment area and the goal of the treatment.

U225 intradermal injector, U225
Which concerns we treat with it
Per concern it says which treatment is used for it. Which one suits you is established by the skin therapist at the intake.
What this device actually does
The U225 is an injector, not a laser and not a device that works on the skin. An air-pressure system pushes an adjustable amount of liquid through a fine needle, at a depth between one and ten millimetres, up to eight times per second.
What sets it apart from injecting by hand is that only the needle moves and the syringe stays still. So there is less vibration and the depth is the same from injection to injection, even when a few hundred follow one another.
What is in the syringe decides the treatment, not the device. That can be a skin booster or a mesotherapy mixture, and that choice belongs with the therapist.
Where this device is meant for
On the left what this device was made for, on the right when something else does more for you.
- Fine lines and laxity
- Hyperpigmentation, sun damage and melasma with a depigmentation booster
- The eye area, with a separate formula
- Building volume the way a filler does
- Removing hair growth
- Pregnancy and breastfeeding
What is different from the other devices here
Several devices here do the same thing to the eye. Which one you get depends on your skin and on what was measured. Below is how they differ from one another.
- Compared with
SkinPen CIT
Pricks to prompt the skin and leaves nothing behind. The U225 puts something in instead.
To the SkinPen CIT - Compared with
Dermapen 4
The same distinction: prompting versus delivering. Anyone wanting ingredients at depth ends up with the U225.
To the Dermapen 4
The concerns this device fits.
Every page below also says what this device is not for, and whether we treat that concern at all.
Frequently asked questions
What exactly does this device do?
It delivers liquid into the skin at a set depth, between one and ten millimetres, up to eight times per second. It is an injector and not a device that works on the skin.
Why not simply inject by hand?
Because only the needle moves and the syringe stays still. So there is less vibration and the depth is the same from injection to injection, even when a few hundred follow one another.
What is in the syringe?
That is decided by the treatment and not the device. It can be a skin booster or a mesotherapy mixture, and that choice belongs with the therapist.
Do I look afterwards as though I have been injected?
Right afterwards you see small bumps where each injection went; those usually settle within a day. Bruises are possible, especially around the eyes, and those last longer.
The difference is in the hand that operates it
The same U225 intradermal injector gives a different result in two clinics. What counts is the measurement beforehand, the setting that belongs with it and the therapist who judges what suits your skin.
The measurement
Under UV and in normal light, so that you know what is there and how deep.
The setting
Strength, depth and pulse duration are chosen for your skin, not to a standard.
The honest no
If this does not fit what is going on with you, we say so.
